Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761986 | 0.80 | KLK5 (0.50) | LMNANCOA3KLK5FFAR1NPC1 | |
| SCHEMBL28198079 | 0.79 | KLK5 (0.49) | LMNANCOA3KLK5FFAR1NPC1 | |
| SCHEMBL4353465 | 0.78 | KLK5 (0.51) | LMNANCOA3KLK5FFAR1NPC1 | |
| SCHEMBL28114917 | 0.77 | FFAR1 (0.42) | LMNANCOA3KLK5FFAR1NPC1 | |
| SCHEMBL27220785 | 0.77 | KLK5 (0.53) | LMNANCOA3KLK5FFAR1NPC1 | |
| SCHEMBL28855596 | 0.76 | KLK5 (0.47) | LMNANCOA3KLK5FFAR1NPC1 | |
| SCHEMBL2230387 | 0.75 | KLK5 (0.49) | LMNANCOA3KLK5FFAR1NPC1 | |
| SCHEMBL5716801 | 0.75 | KLK5 (0.49) | LMNANCOA3KLK5FFAR1NPC1 | |
| SCHEMBL523707 | 0.75 | KLK5 (0.49) | LMNANCOA3KLK5FFAR1NPC1 | |
| SCHEMBL231952 | 0.74 | KLK5 (0.51) | LMNANCOA3KLK5FFAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627672-B | Preparation method of dimemorfan phosphate and intermediate thereof | 广东东阳光药业有限公司 | 2023-01-31 | — | — | CN | disclosed |