Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30179191 | 1.00 | DRD2 (0.56) | DRD2HTR1AOPRM1 | |
| SCHEMBL29324627 | 0.86 | DRD2 (0.61) | DRD2HTR1A | |
| SCHEMBL29325061 | 0.86 | DRD2 (0.46) | DRD2HTR1A | |
| SCHEMBL29324093 | 0.86 | DRD2 (0.50) | DRD2HTR1A | |
| SCHEMBL29323098 | 0.84 | DRD2 (0.62) | DRD2 | |
| SCHEMBL30179173 | 0.84 | DRD2 (0.48) | DRD2HTR1A | |
| SCHEMBL29322785 | 0.84 | DRD2 (0.48) | DRD2HTR1A | |
| SCHEMBL29325040 | 0.83 | DRD2 (0.44) | DRD2HTR1A | |
| SCHEMBL29322794 | 0.83 | DRD2 (0.44) | DRD2HTR1A | |
| SCHEMBL29323645 | 0.82 | DRD2 (0.58) | DRD2HTR1AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400504-A1 | THIOPHENE RING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CN) | 2024-07-17 | — | — | EP | disclosed |
| EP-4400504-A1 | THIOPHENE RING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CN) | 2024-07-17 | — | — | EP | disclosed |
| CN-115772175-A | Thieno-ring compounds, process for their preparation and their use | 中国科学院分子细胞科学卓越创新中心 | 2023-03-10 | — | — | CN | disclosed |