Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.58 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29323098 | 0.84 | DRD2 (0.62) | DRD2SLC6A4DRD3 | |
| SCHEMBL29324093 | 0.84 | DRD2 (0.50) | DRD2HTR1ADRD4DRD3 | |
| SCHEMBL29324627 | 0.84 | DRD2 (0.61) | DRD2SIGMAR1TP53HTR1ADRD4 | |
| SCHEMBL29322785 | 0.82 | DRD2 (0.48) | DRD2HTR1ADRD3 | |
| SCHEMBL30179191 | 0.82 | DRD2 (0.56) | DRD2HTR1AOPRM1 | |
| SCHEMBL28967714 | 0.82 | DRD2 (0.56) | DRD2HTR1AOPRM1 | |
| SCHEMBL30179173 | 0.82 | DRD2 (0.48) | DRD2HTR1ADRD3 | |
| SCHEMBL29324116 | 0.81 | DRD2 (0.51) | DRD2 | |
| SCHEMBL29325061 | 0.81 | DRD2 (0.46) | DRD2SIGMAR1HTR1ADRD4DRD3 | |
| SCHEMBL29322794 | 0.78 | DRD2 (0.44) | DRD2SIGMAR1HTR1ADRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400504-A1 | THIOPHENE RING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CN) | 2024-07-17 | — | — | EP | disclosed |