Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2809700 | 0.74 | HTR2C (0.56) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL289680 | 0.67 | KDM4E (0.60) | ALDH1A1MAPTRAB9AKDM4ERXFP1 | |
| SCHEMBL10301440 | 0.66 | MAPT (0.56) | ALDH1A1MAPTRAB9AKDM4ERXFP1 | |
| SCHEMBL22466257 | 0.65 | SNCA (0.43) | ALDH1A1MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL12131271 | 0.64 | MAPT (0.41) | ALDH1A1MAPTRAB9AKDM4ERXFP1 | |
| SCHEMBL299865 | 0.63 | KDM4E (0.45) | ALDH1A1MAPTRAB9AKDM4ERXFP1 | |
| SCHEMBL22465892 | 0.63 | APP (0.49) | ALDH1A1MAPTKDM4EL3MBTL1MEN1 | |
| SCHEMBL289847 | 0.62 | KDM4E (0.64) | ALDH1A1MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL10186730 | 0.62 | KDM4E (0.61) | ALDH1A1MAPTRAB9AKDM4ERXFP1 | |
| SCHEMBL289855 | 0.62 | MAPT (0.44) | ALDH1A1MAPTRAB9AKDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |