Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289680 | 0.79 | KDM4E (0.60) | HPGDPOLBALDH1A1KDM4EKMT2A | |
| SCHEMBL289671 | 0.78 | HTR2C (0.57) | HTR2CCNR1THRATHRBCES2 | |
| SCHEMBL12789540 | 0.76 | CNR1 (0.77) | HTR2CCNR1HPGDTHRATHRB | |
| SCHEMBL1426839 | 0.74 | ALDH1A1 (0.52) | HTR2CCNR1HPGDPOLBTHRA | |
| SCHEMBL289686 | 0.74 | ALDH1A1 (0.41) | HPGDPOLBALDH1A1KDM4EKMT2A | |
| SCHEMBL289847 | 0.74 | KDM4E (0.64) | HPGDALDH1A1KDM4EMAPT | |
| SCHEMBL298961 | 0.73 | NPC1 (0.62) | HPGDPOLBALDH1A1KDM4EKMT2A | |
| SCHEMBL11400804 | 0.72 | CYP1A2 (0.65) | HTR2CCNR1THRATHRBCES2 | |
| SCHEMBL11384105 | 0.72 | CYP1A2 (0.64) | HTR2CCNR1HPGDTHRATHRB | |
| SCHEMBL29944007 | 0.71 | ALDH1A1 (0.59) | HTR2CCNR1HPGDTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |