Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | BLM | P54132 | 2/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | THPO | P40225 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897824 | 0.94 | MEN1 (0.72) | MEN1MAPTBLMPMP22KMT2A | |
| SCHEMBL2897113 | 0.91 | MEN1 (0.56) | MEN1MAPTBLMPMP22KMT2A | |
| SCHEMBL2904239 | 0.88 | MEN1 (0.54) | MEN1MAPTBLMPMP22KMT2A | |
| SCHEMBL1052855 | 0.83 | MEN1 (0.87) | MEN1MAPTBLMPMP22KMT2A | |
| SCHEMBL2899678 | 0.81 | MEN1 (0.48) | MEN1MAPTBLMPMP22KMT2A | |
| SCHEMBL2905537 | 0.79 | MEN1 (0.47) | MEN1MAPTBLMPMP22KMT2A | |
| SCHEMBL5927862 | 0.78 | MEN1 (0.69) | MEN1MAPTBLMPMP22KMT2A | |
| Tracazolate SCHEMBL114769 | 0.77 | MEN1 (1.00) | MEN1MAPTBLMPMP22KMT2A | |
| Tracazolate SCHEMBL1061780 | 0.76 | MEN1 (0.98) | MEN1MAPTBLMPMP22KMT2A | |
| SCHEMBL2905019 | 0.75 | PDE4B (0.70) | MEN1MAPTBLMPMP22KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982704-B1 | New molecular target of neurotoxicity | EXONHIT THERAPEUTICS SA (FR) | 2010-08-04 | — | — | EP | claimed |