Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 4/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30306805 | 0.91 | HDAC1 (0.40) | MDM4TP53SLC17A5NPC1RAB9A | |
| SCHEMBL28969036 | 0.82 | MDM4 (0.46) | MDM4TP53NPC1RAB9ACASP1 | |
| SCHEMBL28969035 | 0.82 | MDM4 (0.46) | MDM4TP53NPC1RAB9ACASP1 | |
| SCHEMBL28968992 | 0.82 | TLR2 (0.46) | RAB9ATLR2 | |
| SCHEMBL28968954 | 0.81 | TLR2 (0.47) | TLR2 | |
| SCHEMBL28969074 | 0.80 | SLC17A5 (0.45) | MDM4TP53SLC17A5NPC1RAB9A | |
| SCHEMBL28969076 | 0.80 | SLC17A5 (0.45) | MDM4TP53SLC17A5NPC1RAB9A | |
| SCHEMBL30306867 | 0.80 | SLC17A5 (0.45) | MDM4TP53SLC17A5NPC1RAB9A | |
| SCHEMBL20526770 | 0.79 | MDM4 (0.47) | MDM4TP53SLC17A5CASP3MDM2 | |
| SCHEMBL20526767 | 0.79 | MDM4 (0.47) | MDM4TP53SLC17A5CASP3MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666553-A | TLR2 modulator compounds, and pharmaceutical compositions and uses thereof | 轴向治疗公司 | 2023-01-31 | — | — | CN | disclosed |