Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28968954 | 0.99 | TLR2 (0.47) | TLR2KMT2ATNF | |
| SCHEMBL30306748 | 0.92 | TLR2 (0.43) | TLR2KMT2A | |
| SCHEMBL28968885 | 0.82 | MDM4 (0.40) | TLR2RAB9A | |
| SCHEMBL28968965 | 0.80 | GRIA1 (0.47) | RAB9A | |
| SCHEMBL30306884 | 0.80 | GRIA1 (0.47) | RAB9A | |
| SCHEMBL28969074 | 0.79 | SLC17A5 (0.45) | TNFRAB9A | |
| SCHEMBL28969076 | 0.79 | SLC17A5 (0.45) | TNFRAB9A | |
| SCHEMBL30306867 | 0.79 | SLC17A5 (0.45) | TNFRAB9A | |
| SCHEMBL20526770 | 0.77 | MDM4 (0.47) | TNF | |
| SCHEMBL20526767 | 0.77 | MDM4 (0.47) | TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666553-A | TLR2 modulator compounds, and pharmaceutical compositions and uses thereof | 轴向治疗公司 | 2023-01-31 | — | — | CN | disclosed |