Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 7/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.50 |
| ▸ | RARB | P10826 | 5/20 | 0.49 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | RRM1 | P23921 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28968982 | 1.00 | CSNK2A2 (0.50) | CSNK2A2CSNK2A1RARBRARGCSNK2B | |
| SCHEMBL25022268 | 0.90 | MGLL (0.46) | CSNK2A2CSNK2A1RARBRARGRRM1 | |
| SCHEMBL30306958 | 0.84 | GRIA1 (0.49) | CSNK2A2CSNK2A1RARBRARG | |
| SCHEMBL28968916 | 0.84 | GRIA1 (0.49) | CSNK2A2CSNK2A1RARBRARG | |
| SCHEMBL25022249 | 0.81 | CSNK2A2 (0.44) | CSNK2A2CSNK2A1RARBRARGCSNK2B | |
| SCHEMBL28969088 | 0.78 | HDAC8 (0.45) | RARBRARGRRM1ALDH1A1DPP7 | |
| SCHEMBL28969078 | 0.78 | HDAC8 (0.45) | RARBRARGRRM1ALDH1A1DPP7 | |
| SCHEMBL10421798 | 0.78 | RARB (0.61) | CSNK2A2CSNK2A1RARBCSNK2BMEN1 | |
| SCHEMBL28968977 | 0.75 | RARB (0.42) | RARBRARGRRM1DPP7 | |
| SCHEMBL28968974 | 0.75 | RARB (0.42) | RARBRARGRRM1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666553-A | TLR2 modulator compounds, and pharmaceutical compositions and uses thereof | 轴向治疗公司 | 2023-01-31 | — | — | CN | disclosed |