Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RRM1 | P23921 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28969088 | 1.00 | HDAC8 (0.45) | HDAC8HDAC1HDAC2RARBRARG | |
| SCHEMBL24073346 | 0.90 | MGLL (0.46) | HDAC8HDAC1HDAC2RRM1DPP7 | |
| SCHEMBL28969089 | 0.87 | RARB (0.44) | HDAC8HDAC1HDAC2RARBRARG | |
| SCHEMBL28969082 | 0.87 | RARB (0.44) | HDAC8HDAC1HDAC2RARBRARG | |
| SCHEMBL28968987 | 0.84 | GRIA1 (0.47) | RARBRARGKDM4EALDH1A1HPGD | |
| SCHEMBL30306849 | 0.84 | GRIA1 (0.47) | RARBRARGKDM4EALDH1A1HPGD | |
| SCHEMBL28968977 | 0.83 | RARB (0.42) | HDAC1RARBRARGRRM1DPP7 | |
| SCHEMBL28968974 | 0.83 | RARB (0.42) | HDAC1RARBRARGRRM1DPP7 | |
| SCHEMBL28968982 | 0.78 | CSNK2A2 (0.50) | RARBRARGALDH1A1RRM1DPP7 | |
| SCHEMBL28968979 | 0.78 | CSNK2A2 (0.50) | RARBRARGALDH1A1RRM1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666553-A | TLR2 modulator compounds, and pharmaceutical compositions and uses thereof | 轴向治疗公司 | 2023-01-31 | — | — | CN | disclosed |