Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1823760 | 0.78 | CYP19A1 (0.42) | CYP19A1CYP3A4CYP2C19KDM4ECYP11B1 | |
| SCHEMBL14860915 | 0.77 | CYP1A2 (0.43) | CYP3A4CYP2C19KDM4ETSHRALDH1A1 | |
| SCHEMBL3736492 | 0.75 | CYP2A6 (0.45) | CYP19A1CYP3A4CYP2C19KDM4ECYP11B1 | |
| SCHEMBL7237526 | 0.74 | KDM4E (0.40) | KDM4EALDH1A1LMNA | |
| SCHEMBL28093362 | 0.74 | SMN1; SMN2 (0.41) | CYP19A1CYP2C19KDM4ECYP11B2ALDH1A1 | |
| SCHEMBL1507838 | 0.73 | CYP1A2 (0.40) | CYP3A4CYP2C19KDM4ETSHRALDH1A1 | |
| SCHEMBL1842982 | 0.73 | KDM4E (0.51) | CYP19A1CYP3A4CYP2C19KDM4EALDH1A1 | |
| SCHEMBL20335430 | 0.73 | CYP1A2 (0.40) | CYP19A1CYP3A4CYP2C19S1PR3CYP1A2 | |
| SCHEMBL5475832 | 0.73 | S1PR3 (0.45) | CYP19A1KDM4EALDH1A1S1PR3 | |
| SCHEMBL2526423 | 0.73 | CYP3A4 (0.41) | CYP19A1CYP3A4CYP2C19KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | CYP19A1 726/4885CYP3A4 87/4885CYP2C19 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.