Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.36 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234254 | 0.83 | CYP19A1 (0.39) | CYP19A1KDM4ELMNACYP2A6SMN1; SMN2 | |
| SCHEMBL3736492 | 0.79 | CYP2A6 (0.45) | CYP19A1KDM4ELMNACYP2A6SMN1; SMN2 | |
| SCHEMBL2896902 | 0.78 | CYP19A1 (0.33) | CYP19A1KDM4ELMNACYP2A6SMN1; SMN2 | |
| SCHEMBL20335430 | 0.77 | CYP1A2 (0.40) | CYP19A1CYP3A4CYP2C19 | |
| SCHEMBL2076101 | 0.77 | S1PR3 (0.41) | CYP19A1KDM4ELMNAALDH1A1TSHR | |
| SCHEMBL25077137 | 0.77 | P2RX3 (0.42) | CYP19A1KDM4ECYP3A4CYP11B1CYP11B2 | |
| SCHEMBL5475832 | 0.77 | S1PR3 (0.45) | CYP19A1KDM4EALDH1A1 | |
| SCHEMBL25077473 | 0.77 | CYP19A1 (0.36) | CYP19A1KDM4ECYP2A6SMN1; SMN2ALDH1A1 | |
| SCHEMBL1842982 | 0.77 | KDM4E (0.51) | CYP19A1KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL2526423 | 0.77 | CYP3A4 (0.41) | CYP19A1KDM4EALDH1A1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139477-A1 | PYRAZOLO PYRIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYO TEX SA (CH) | 2010-01-06 | — | — | EP | claimed |
| WO-2008113856-A1 | PYRAZOLO PYRIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYO TEX SA (CH) | 2008-09-25 | — | — | WO | claimed |
| US-12528780-B2 | 2-(1,2,4-triazolyl) benzoyl arylamine active compound for inhibiting wheat take-all pathogen | HENAN AGRICULTURAL UNIVERSITY (CN) | 2026-01-20 | — | — | US | disclosed |
| WO-2025124407-A1 | PYRAZOLE-SUBSTITUTED ARYL SULFIDE COMPOUND AND USE THEREOF | 青岛清原化合物有限公司 | 2025-06-19 | — | — | WO | disclosed |
| CN-115246826-B | Quaternary ammonium salt isoxazoline compound, its preparation and application as insecticidal and bactericidal agent | 瑞普（天津）生物药业有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117858881-A | Phospholipid compounds and methods of making and using the same | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-112771034-B | Heteroaryl azole compound and pest control agent | 日本曹达株式会社 | 2024-02-09 | — | — | CN | disclosed |
| US-20220348550-A1 | 2-(1,2,4-TRIAZOLYL) BENZOYL ARYLAMINE ACTIVE COMPOUND FOR INHIBITING WHEAT TAKE-ALL PATHOGEN | HENAN AGRICULTURAL UNIVERSITY (CN) | 2022-11-03 | — | — | US | disclosed |
| CN-114980742-A | Composition for agricultural or horticultural use | 日本曹达株式会社 | 2022-08-30 | — | — | CN | disclosed |
| CN-111741681-B | Agricultural and horticultural bactericide composition | 日本曹达株式会社 | 2022-07-19 | — | — | CN | disclosed |
| CN-109689630-B | Diaryl azole compound and pest control agent | 日本曹达株式会社 | 2022-06-03 | — | — | CN | disclosed |
| US-20040097730-A1 | Thrombin inhibitors | MERCK & CO., INC. | 2004-05-20 | — | — | US | disclosed |
| US-20040073025-A1 | Thrombin inhibitors | MERCK SHARP & DOHME CORP. | 2004-04-15 | — | — | US | disclosed |
| EP-1359913-A1 | THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-6610701-B2 | For therapy and prophylaxis of blood coagulation and cardiovascular disorders | MERCK & CO., INC. | 2003-08-26 | — | — | US | disclosed |
| US-20030158218-A1 | Thrombin inhibitors | NANTERMET PHILIPPE G (US) | 2003-08-21 | — | — | US | disclosed |
| US-20020193398-A1 | Thrombin inhibitors | MERCK & CO., INC. | 2002-12-19 | — | — | US | disclosed |
| WO-2002064211-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-08-22 | — | — | WO | disclosed |
| WO-2002064140-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-08-22 | — | — | WO | disclosed |
| WO-2002064559-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220348550-A1 | 2-(1,2,4-TRIAZOLYL) BENZOYL ARYLAMINE ACTIVE COMPOUND FOR INHIBITING WHEAT TAKE-ALL PATHOGEN | THEM6, HRH4, CBR3 | CYP19A1 3977/4885KDM4E 891/4885LMNA 3168/4885 |
| US-20040097730-A1 | Thrombin inhibitors | F3, F2, SERPINC1 | CYP19A1 2407/4885KDM4E 3645/4885LMNA 4332/4885 |
| US-20030158218-A1 | Thrombin inhibitors | F2, SERPINC1, TFPI | CYP19A1 2045/4885KDM4E 4360/4885LMNA 3043/4885 |
| US-20020193398-A1 | Thrombin inhibitors | F2, F3, TFPI | CYP19A1 1490/4885KDM4E 3146/4885LMNA 1368/4885 |
| US-12528780-B2 | 2-(1,2,4-triazolyl) benzoyl arylamine active compound for inhibiting wheat take-all pathogen | CBR3, GET3, HRH4 | CYP19A1 4378/4885KDM4E 1257/4885LMNA 2531/4885 |
| US-20040073025-A1 | Thrombin inhibitors | F2, F11, F10 | CYP19A1 2077/4885KDM4E 3151/4885LMNA 1769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.