SCHEMBL2896903

SCHEMBL2896903

CC(=O)NC[C@H]1CN(c2cc(F)c(-c3ccc(-c4nnn(C)n4)nc3)c(F)c2)C(=O)O1

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOA P21397 8/20 0.67
MAOB P27338 3/20 0.67
PTGS1 P23219 2/20 0.49
SDHA P31040 2/20 0.49
LMNA P02545 1/20 0.49
CALML3 P27482 1/20 0.49
ABCB11 O95342 1/20 0.42
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
F10 P00742 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6625769 0.91 MAOA (0.81) MAOAMAOBPTGS1SDHALMNA
SCHEMBL2898109 0.90 MAOA (0.54) MAOAMAOBPTGS1SDHALMNA
SCHEMBL1381525 0.89 MAOA (0.82) MAOAMAOBCALML3CYP2C9CYP2C19
SCHEMBL2899787 0.87 MAOA (0.50) MAOAMAOBPTGS1SDHALMNA
SCHEMBL2895240 0.87 MAOA (0.57) MAOAMAOBPTGS1SDHALMNA
SCHEMBL2894852 0.85 MAOA (0.61) MAOAMAOBCALML3CYP2C9CYP2C19
SCHEMBL2898311 0.84 MAOA (0.60) MAOAMAOBCALML3CYP2C9CYP2C19
SCHEMBL2891597 0.84 MAOA (0.51) MAOAMAOBPTGS1SDHALMNA
SCHEMBL13089900 0.83 MAOA (0.77) MAOAMAOBCALML3CYP2C9CYP2C19
SCHEMBL25808578 0.83 MAOA (0.68) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US claimed
EP-1799677-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS Ranbaxy Laboratories Limited (IN) 2007-06-27 EP claimed
WO-2006038100-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2006-04-13 WO claimed
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US disclosed
EP-1799677-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS Ranbaxy Laboratories Limited (IN) 2007-06-27 EP disclosed
WO-2006038100-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2006-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS OXA1L, PDK4, MLYCD MAOA 1717/4885MAOB 2038/4885PTGS1 3182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.