Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 5/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511933 | 0.80 | CNR2 (0.46) | BCHECNR2TACR1CA12CA1 | |
| SCHEMBL29227306 | 0.80 | CNR2 (0.46) | BCHECNR2TACR1CA12CA1 | |
| SCHEMBL28291781 | 0.79 | CA12 (0.35) | BCHECNR2GNAI3GNAO1GNAI1 | |
| SCHEMBL28291785 | 0.79 | CA12 (0.35) | BCHECNR2GNAI3GNAO1GNAI1 | |
| SCHEMBL7715030 | 0.79 | NAAA (0.49) | TACR1GNAI3GNAO1GNAI1EPHX1 | |
| SCHEMBL7713393 | 0.79 | NAAA (0.49) | TACR1GNAI3GNAO1GNAI1EPHX1 | |
| Hydrochloric Acid SCHEMBL28629335 | 0.78 | GNAI3 (0.35) | BCHECNR2GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL28290328 | 0.78 | GNAI3 (0.35) | BCHECNR2GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL28290340 | 0.78 | GNAI3 (0.35) | BCHECNR2GNAI3GNAO1GNAI1 | |
| SCHEMBL31131445 | 0.76 | NAAA (0.46) | TACR1GNAI3GNAO1GNAI1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666553-A | TLR2 modulator compounds, and pharmaceutical compositions and uses thereof | 轴向治疗公司 | 2023-01-31 | — | — | CN | disclosed |