Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NQO2 | P16083 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929165 | 0.79 | ALDH1A1 (0.39) | HTTALDH1A1PFKFB3PTPN1MTNR1A | |
| SCHEMBL28969311 | 0.78 | EGFR (0.34) | — | |
| SCHEMBL18330776 | 0.78 | ALDH1A1 (0.38) | HTTALDH1A1PFKFB3PTPN1MTNR1A | |
| SCHEMBL30211117 | 0.76 | ALDH1A1 (0.42) | HTTALDH1A1PFKFB3PTPN1MAPT | |
| SCHEMBL18330811 | 0.76 | ALDH1A1 (0.42) | HTTALDH1A1PFKFB3PTPN1MAPT | |
| SCHEMBL9844197 | 0.72 | PTPN1 (0.47) | HTTALDH1A1PFKFB3PTPN1MTNR1A | |
| SCHEMBL29592044 | 0.72 | PTPN1 (0.47) | HTTALDH1A1PFKFB3PTPN1MTNR1A | |
| SCHEMBL9843978 | 0.68 | HTT (0.47) | HTTALDH1A1PTPN1MAPTSMN1; SMN2 | |
| SCHEMBL21954375 | 0.68 | PTPN1 (0.46) | HTTALDH1A1PTPN1MAPTSMN1; SMN2 | |
| SCHEMBL29591394 | 0.68 | PTPN1 (0.46) | HTTALDH1A1PTPN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667275-B | Boron-containing compounds and uses thereof | 南京再明医药有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-115667275-A | Boron-containing compounds and their use | 先声药业有限公司 | 2023-01-31 | — | — | CN | disclosed |