Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17378987 | 0.85 | MAPT (0.38) | PTPN1ALDH1A1HTTMAPTSMN1; SMN2 | |
| SCHEMBL9844197 | 0.83 | PTPN1 (0.47) | PTPN1ALDH1A1HTTMEN1MAPT | |
| SCHEMBL9843978 | 0.81 | HTT (0.47) | PTPN1ALDH1A1HTTMEN1MAPT | |
| SCHEMBL15898858 | 0.79 | PTPN1 (0.47) | PTPN1ALDH1A1HTTMAPTHTR1A | |
| SCHEMBL8189977 | 0.79 | ALDH1A1 (0.45) | PTPN1ALDH1A1HTTHTR1AHTR1D | |
| SCHEMBL8950172 | 0.79 | HTR1A (0.59) | PTPN1ALDH1A1HTTHTR1AHTR1D | |
| SCHEMBL6608694 | 0.78 | PTPN1 (0.46) | PTPN1HTTKMT2AHTR1AHTR1D | |
| SCHEMBL8950321 | 0.77 | CSNK2A1 (0.50) | PTPN1ALDH1A1HTTMEN1MAPT | |
| SCHEMBL21591484 | 0.76 | MAPT (0.44) | PTPN1ALDH1A1HTTMAPTMAOB | |
| SCHEMBL8950005 | 0.75 | HTR1A (0.60) | PTPN1ALDH1A1HTTHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12558341-B2 | Oral complement factor D inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-20250186391-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2025-06-12 | — | — | US | disclosed |
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| EP-3717467-A1 | BENZENE FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | Taiwanj Pharmaceuticals Co., Ltd. (TW) | 2020-10-07 | — | — | EP | disclosed |
| CN-111491928-A | Benzoheterocyclic compounds and uses thereof | 景凱生物科技股份有限公司 | 2020-08-04 | — | — | CN | disclosed |
| US-20200157088-A1 | BENZENE FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | TAIWANJ PHARMACEUTICALS CO., LTD. (TW) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12558341-B2 | Oral complement factor D inhibitors | CFD, CFH, CFB | PTPN1 3533/4885ALDH1A1 2667/4885HTT 2238/4885 |
| US-20200157088-A1 | BENZENE FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | NR2C2, NR0B2, NR0B1 | PTPN1 1849/4885ALDH1A1 1062/4885HTT 3447/4885 |
| US-20250186391-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | CFD, CFH, CFB | PTPN1 3369/4885ALDH1A1 3142/4885HTT 3291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.