Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | DRD1 | P21728 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL841913 | 0.87 | DRD2 (0.51) | DRD2DRD3CYP1A2CYP2D6TSHR | |
| SCHEMBL841912 | 0.87 | DRD2 (0.51) | DRD2DRD3CYP1A2CYP2D6TSHR | |
| SCHEMBL841199 | 0.87 | DRD2 (0.51) | DRD2DRD3CYP1A2CYP2D6TSHR | |
| SCHEMBL7104915 | 0.72 | DRD2 (0.59) | DRD2DRD3DRD1CYP1A2CYP3A4 | |
| SCHEMBL7024427 | 0.72 | DRD2 (0.68) | DRD2DRD3DRD1CYP1A2CYP3A4 | |
| SCHEMBL7020915 | 0.72 | DRD2 (0.59) | DRD2DRD3DRD1CYP1A2CYP3A4 | |
| SCHEMBL7029720 | 0.72 | DRD2 (0.68) | DRD2DRD3DRD1CYP1A2CYP3A4 | |
| SCHEMBL7022473 | 0.72 | DRD2 (0.59) | DRD2DRD3DRD1CYP1A2CYP3A4 | |
| SCHEMBL12128220 | 0.72 | DRD3 (0.58) | DRD2DRD3TSHRSLC6A2SLC6A4 | |
| SCHEMBL7026910 | 0.70 | DRD2 (0.84) | DRD2DRD3DRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806561-A | JAK3 selective inhibitors and uses thereof | 南京药石科技股份有限公司 | 2023-03-17 | — | — | CN | disclosed |