Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | IRAK4 | Q9NWZ3 | 9/20 | 0.67 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28598419 | 0.86 | HPGD (0.63) | HDAC6IRAK4TLR7RAB9AMAPK1 | |
| SCHEMBL7703958 | 0.85 | IRAK4 (0.66) | HDAC6IRAK4TLR7HDAC2NPC1 | |
| SCHEMBL28348308 | 0.85 | HDAC6 (0.65) | HDAC6IRAK4TLR7HDAC2NPC1 | |
| SCHEMBL28344825 | 0.84 | IRAK4 (0.68) | HDAC6IRAK4TLR7HDAC2NPC1 | |
| SCHEMBL28970478 | 0.83 | HDAC6 (0.78) | HDAC6IRAK4TLR7HDAC2NPC1 | |
| SCHEMBL14426771 | 0.82 | IRAK4 (0.69) | HDAC6IRAK4TLR7HDAC2NPC1 | |
| SCHEMBL3477450 | 0.82 | HDAC6 (0.67) | HDAC6IRAK4TLR7HDAC2NPC1 | |
| SCHEMBL17175809 | 0.82 | IRAK4 (0.69) | HDAC6IRAK4TLR7HDAC2NPC1 | |
| SCHEMBL2113234 | 0.82 | HDAC6 (0.67) | HDAC6IRAK4TLR7HDAC2NPC1 | |
| SCHEMBL24755152 | 0.82 | HDAC6 (1.00) | HDAC6IRAK4TLR7HDAC2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |