SCHEMBL28970495

SCHEMBL28970495

COc1ccc(C2(O)CCCCCCC2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 6/20 0.54
SLC6A3 Q01959 6/20 0.54
GRIN1 Q05586 1/20 0.54
GRIN2A Q12879 1/20 0.54
GRIN2B Q13224 1/20 0.54
OPRM1 P35372 2/20 0.54
OPRD1 P41143 2/20 0.54
OPRK1 P41145 2/20 0.54
OPRL1 P41146 2/20 0.54
HRH3 Q9Y5N1 4/20 0.50
HSD11B1 P28845 1/20 0.49
LMNA P02545 3/20 0.48
MEN1 O00255 2/20 0.48
ALDH1A1 P00352 2/20 0.48
KMT2A Q03164 2/20 0.48
TSHR P16473 2/20 0.48
POLB P06746 1/20 0.48
HTT P42858 1/20 0.48
HSD17B10 Q99714 1/20 0.48
SLC6A2 P23975 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28970493 1.00 SLC6A4 (0.54) SLC6A4SLC6A3GRIN1GRIN2AGRIN2B
SCHEMBL21874209 1.00 SLC6A4 (0.54) SLC6A4SLC6A3GRIN1GRIN2AGRIN2B
SCHEMBL29151340 1.00 SLC6A4 (0.54) SLC6A4SLC6A3GRIN1GRIN2AGRIN2B
SCHEMBL2778410 1.00 SLC6A4 (0.54) SLC6A4SLC6A3GRIN1GRIN2AGRIN2B
SCHEMBL28970507 1.00 SLC6A4 (0.54) SLC6A4SLC6A3GRIN1GRIN2AGRIN2B
SCHEMBL29151325 1.00 SLC6A4 (0.54) SLC6A4SLC6A3GRIN1GRIN2AGRIN2B
SCHEMBL12317609 0.98 OPRM1 (0.55) SLC6A4SLC6A3GRIN1GRIN2AGRIN2B
SCHEMBL10319703 0.94 OPRM1 (0.55) SLC6A4SLC6A3GRIN1GRIN2AGRIN2B
SCHEMBL31556366 0.83 HRH3 (0.49) OPRM1OPRD1OPRK1OPRL1HRH3
SCHEMBL18244775 0.82 OPRM1 (0.53) SLC6A4SLC6A3GRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117185966-B Method for carrying out open-loop sulfonylation on cycloalkanol 安徽金桐精细化学有限公司 2024-09-24 CN disclosed
CN-117185966-A Method for carrying out open-loop sulfonylation on cycloalkanol 安徽金桐精细化学有限公司 2023-12-08 CN disclosed
CN-115806488-A Method for ring-opening allylation of cycloalkanol 南京工业大学 2023-03-17 CN disclosed