Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17606417 | 0.82 | SSTR3 (0.46) | MEN1KMT2ABACE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL17606418 | 0.82 | SSTR3 (0.46) | MEN1KMT2ABACE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31687192 | 0.81 | MAPT (0.43) | MEN1KMT2AALDH1A1 | |
| SCHEMBL30255307 | 0.81 | MAPT (0.43) | MEN1KMT2AALDH1A1 | |
| SCHEMBL31455109 | 0.81 | MAPT (0.43) | MEN1KMT2AALDH1A1 | |
| SCHEMBL31455176 | 0.81 | MAPT (0.43) | MEN1KMT2AALDH1A1 | |
| SCHEMBL31455549 | 0.79 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL31455336 | 0.79 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL31455570 | 0.77 | DPP4 (0.37) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL31455326 | 0.77 | DPP4 (0.37) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4620951-A1 | MEMANTINE UREA DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN PREPARATION OF MEDICAMENT FOR TREATING SOLUBLE EPOXIDE ENZYME-MEDIATED DISEASES | Shenyang Pharmaceutical University (CN) | 2025-09-24 | — | — | EP | disclosed |
| CN-115819328-B | Memantine urea derivatives, preparation method thereof and application thereof in preparation of medicines for treating soluble epoxide enzyme mediated diseases | 沈阳药科大学 | 2024-08-27 | — | — | CN | disclosed |
| CN-115819328-A | Memantine urea derivative, preparation method thereof and application thereof in preparing medicine for treating soluble epoxide hydrolase mediated diseases | 沈阳药科大学 | 2023-03-21 | — | — | CN | disclosed |