Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31687192 | 1.00 | MAPT (0.43) | MAPTPOLBTDP1ALDH1A1MAPK1 | |
| SCHEMBL31455109 | 1.00 | MAPT (0.43) | MAPTPOLBTDP1ALDH1A1MAPK1 | |
| SCHEMBL30255307 | 1.00 | MAPT (0.43) | MAPTPOLBTDP1ALDH1A1MAPK1 | |
| SCHEMBL31455422 | 0.88 | MAPT (0.44) | MAPTPOLBTDP1ALDH1A1MAPK1 | |
| SCHEMBL28972001 | 0.81 | MEN1 (0.42) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL30289535 | 0.81 | MAPT (0.56) | MAPTPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL31455344 | 0.81 | MAPT (0.43) | MAPTTDP1ALDH1A1MAPK1KDM4E | |
| SCHEMBL31455401 | 0.81 | MAPT (0.43) | MAPTTDP1ALDH1A1MAPK1KDM4E | |
| SCHEMBL31455310 | 0.79 | MAPT (0.42) | MAPTTDP1ALDH1A1MAPK1KDM4E | |
| SCHEMBL31455436 | 0.79 | MAPT (0.42) | MAPTTDP1ALDH1A1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |