Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 10/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30061974 | 1.00 | LMNA (0.49) | LMNANPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL28972166 | 0.83 | NPC1 (0.60) | LMNANPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL28972163 | 0.82 | LMNA (0.48) | LMNANPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL30063917 | 0.82 | LMNA (0.48) | LMNANPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL28972167 | 0.80 | MAPK1 (0.51) | LMNANPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL30218942 | 0.80 | MAPK1 (0.51) | LMNANPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL28972136 | 0.80 | KDM4E (0.63) | LMNANPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL30061959 | 0.80 | KDM4E (0.63) | LMNANPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL30063964 | 0.80 | MAPK1 (0.66) | LMNANPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL28972206 | 0.80 | MAPK1 (0.66) | LMNANPC1RAB9AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667224-A | SCL15A4 small molecule inhibitors with anti-inflammatory activity | 斯克里普斯研究学院 | 2023-01-31 | — | — | CN | disclosed |