Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 12/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 5/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30063917 | 1.00 | LMNA (0.48) | LMNATDP1BRD4CYP2C9SMN1; SMN2 | |
| SCHEMBL28972296 | 0.83 | RAB9A (0.54) | LMNATDP1SMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL28972179 | 0.82 | LMNA (0.49) | LMNATDP1BRD4CYP2C9SMN1; SMN2 | |
| SCHEMBL30061974 | 0.82 | LMNA (0.49) | LMNATDP1BRD4CYP2C9SMN1; SMN2 | |
| SCHEMBL28972489 | 0.77 | RAB9A (0.49) | LMNATDP1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL28972487 | 0.70 | LMNA (0.45) | LMNATDP1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL30061980 | 0.70 | LMNA (0.45) | LMNATDP1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL28972240 | 0.69 | RAB9A (0.42) | LMNATDP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL31329350 | 0.68 | RAB9A (0.71) | LMNASMN1; SMN2TSHRHIF1AMEN1 | |
| SCHEMBL20362755 | 0.68 | BRD4 (0.52) | LMNABRD4CYP2C9SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667224-A | SCL15A4 small molecule inhibitors with anti-inflammatory activity | 斯克里普斯研究学院 | 2023-01-31 | — | — | CN | disclosed |