Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28972246 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KMT2AL3MBTL1GAAMGAM | |
| SCHEMBL30218920 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KMT2AL3MBTL1GAAMGAM | |
| SCHEMBL28972296 | 0.81 | RAB9A (0.54) | ALDH1A1KMT2AL3MBTL1GAAMGAM | |
| SCHEMBL541005 | 0.78 | KMT2A (0.65) | ALDH1A1KMT2AL3MBTL1NPY5RKDM4E | |
| SCHEMBL541006 | 0.78 | KMT2A (0.65) | ALDH1A1KMT2AL3MBTL1NPY5RKDM4E | |
| SCHEMBL13958870 | 0.77 | KMT2A (0.67) | ALDH1A1KMT2AL3MBTL1NPY5RKDM4E | |
| SCHEMBL541216 | 0.76 | KMT2A (0.57) | ALDH1A1KMT2AL3MBTL1NPY5RKDM4E | |
| SCHEMBL541215 | 0.76 | KMT2A (0.57) | ALDH1A1KMT2AL3MBTL1NPY5RKDM4E | |
| SCHEMBL30523185 | 0.73 | KMT2A (0.61) | ALDH1A1KMT2AL3MBTL1NPY5RKDM4E | |
| SCHEMBL20181195 | 0.73 | KMT2A (0.61) | ALDH1A1KMT2AL3MBTL1NPY5RKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667224-A | SCL15A4 small molecule inhibitors with anti-inflammatory activity | 斯克里普斯研究学院 | 2023-01-31 | — | — | CN | disclosed |