SCHEMBL28972508

SCHEMBL28972508

COc1cc(OC)cc(OB(O)OO)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
CYP1A1 P04798 5/20 0.39
CYP1B1 Q16678 5/20 0.39
TUBB4A P04350 2/20 0.39
TUBB P07437 2/20 0.39
TUBA3C P0DPH7 2/20 0.39
TUBA1B P68363 2/20 0.39
TUBA4A P68366 2/20 0.39
TUBB4B P68371 2/20 0.39
TUBB3 Q13509 2/20 0.39
TUBB2A Q13885 2/20 0.39
TUBB8 Q3ZCM7 2/20 0.39
TUBA3E Q6PEY2 2/20 0.39
TUBA1A Q71U36 2/20 0.39
TUBA1C Q9BQE3 2/20 0.39
TUBB6 Q9BUF5 2/20 0.39
TUBB2B Q9BVA1 2/20 0.39
TUBB1 Q9H4B7 2/20 0.39
CYP3A4 P08684 3/20 0.38
ABL1 P00519 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5207737 0.78 ALDH1A1 (0.58) ALDH1A1CYP1A1CYP1B1TUBB4ATUBB
SCHEMBL28462298 0.77 ALDH1A1 (0.44) ALDH1A1CYP1A1CYP1B1TUBB4ATUBB
SCHEMBL22769689 0.71 ALDH1A1 (0.48) ALDH1A1CYP1A1CYP1B1TUBB4ATUBB
1,3,5-Trimethoxybenzene SCHEMBL28493 0.71 ALDH1A1 (1.00) ALDH1A1CYP1A1CYP1B1TUBB4ATUBB
SCHEMBL30206771 0.70 ALDH1A1 (0.52) ALDH1A1CYP1A1CYP1B1TUBB4ATUBB
SCHEMBL30516653 0.70 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1TUBB4ATUBB
SCHEMBL28080318 0.70 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1TUBB4ATUBB
SCHEMBL8830 0.69 ENPP2 (0.61) ALDH1A1CYP1A1CYP1B1TUBB4ATUBB
1,3,5-Trimethoxybenzene SCHEMBL28557531 0.68 ALDH1A1 (0.92) ALDH1A1CYP1A1CYP1B1TUBB4ATUBB
1,3,5-Trimethoxybenzene SCHEMBL28416912 0.68 ALDH1A1 (0.92) ALDH1A1CYP1A1CYP1B1TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115836053-A Pyrazolone formyl peptide 2 receptor agonists 百时美施贵宝公司 2023-03-21 CN disclosed