Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 1.00 |
| ▸ | HTR1A | P08908 | 4/20 | 0.70 |
| ▸ | HTR2A | P28223 | 3/20 | 0.70 |
| ▸ | DRD3 | P35462 | 2/20 | 0.62 |
| ▸ | DRD4 | P21917 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30206528 | 0.87 | DRD2 (1.00) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL28972657 | 0.83 | DRD2 (1.00) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL28972649 | 0.82 | DRD2 (1.00) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL7693542 | 0.82 | DRD2 (0.70) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL9028512 | 0.80 | KDM4E (0.68) | DRD2HTR1AHTR2ADRD3KDM4E | |
| SCHEMBL28972656 | 0.80 | DRD2 (1.00) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL28972646 | 0.78 | HTR1A (1.00) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL10414460 | 0.78 | DRD2 (1.00) | DRD2HTR1AHTR2ADRD3ALDH1A1 | |
| SCHEMBL5655837 | 0.78 | DRD2 (0.63) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL1491175 | 0.77 | HTR1A (0.71) | DRD2HTR1AHTR2ADRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511215-B | Aryl piperazine/piperidine compound and application thereof | 复旦大学 | 2023-03-28 | — | — | CN | disclosed |