Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 18/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 17/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28972699 | 0.90 | CYP11B2 (0.48) | CYP11B2CYP11B1EGLN2 | |
| SCHEMBL28972450 | 0.86 | CASP1 (0.43) | CYP11B2CYP11B1 | |
| SCHEMBL28972389 | 0.85 | AR (0.48) | — | |
| SCHEMBL28972449 | 0.82 | CYP11B2 (0.43) | CYP11B2CYP11B1EGLN2 | |
| SCHEMBL28972460 | 0.81 | MYC (0.37) | EGLN2 | |
| SCHEMBL28972685 | 0.79 | EGLN2 (0.36) | CYP11B2CYP11B1EGLN2 | |
| SCHEMBL30112095 | 0.79 | EGLN2 (0.36) | CYP11B2CYP11B1EGLN2 | |
| SCHEMBL30112094 | 0.78 | CYP11B2 (0.47) | CYP11B2CYP11B1EGLN2 | |
| SCHEMBL28972439 | 0.78 | EGLN2 (0.38) | CYP11B2CYP11B1EGLN2 | |
| SCHEMBL30112106 | 0.76 | CTSA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016011-B | Amide derivative and medical use thereof | 北京美倍他药物研究有限公司 | 2023-02-03 | — | — | CN | disclosed |