Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 14/20 | 0.50 |
| ▸ | AOC1 | P19801 | 12/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.48 |
| ▸ | MELK | Q14680 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17372010 | 0.81 | AOC3 (0.56) | AOC3AOC1LOXL2MELK | |
| SCHEMBL17372104 | 0.79 | AOC3 (0.47) | AOC3AOC1LOXL2 | |
| SCHEMBL17372528 | 0.79 | AOC3 (0.56) | AOC3AOC1LOXL2 | |
| SCHEMBL26601434 | 0.78 | AOC3 (0.43) | AOC3AOC1LOXL2MELK | |
| SCHEMBL31397851 | 0.78 | AOC3 (0.43) | AOC3AOC1LOXL2MELK | |
| SCHEMBL17371911 | 0.77 | LOXL2 (0.49) | AOC3AOC1LOXL2MELK | |
| SCHEMBL17371994 | 0.77 | LOXL2 (0.49) | AOC3AOC1LOXL2 | |
| SCHEMBL26781479 | 0.77 | AOC3 (0.46) | AOC3AOC1LOXL2MELK | |
| SCHEMBL17372175 | 0.77 | AOC3 (0.46) | AOC3AOC1LOXL2MELK | |
| SCHEMBL29784977 | 0.77 | AOC3 (0.46) | AOC3AOC1LOXL2MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115836070-A | Fused ring compound as EGFR inhibitor and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-03-21 | — | — | CN | disclosed |