Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 2/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29274299 | 0.93 | NR1H2 (0.44) | NR1H2NR1H3GPR119MEN1KMT2A | |
| SCHEMBL29274214 | 0.93 | NR1H2 (0.44) | NR1H2NR1H3GPR119MEN1KMT2A | |
| SCHEMBL29274284 | 0.88 | NR1H2 (0.42) | NR1H2NR1H3GPR119MEN1KMT2A | |
| SCHEMBL31381998 | 0.87 | CXCR3 (0.43) | GPR119MEN1KMT2ACXCR3CYP1A2 | |
| SCHEMBL31382096 | 0.87 | CXCR3 (0.43) | GPR119MEN1KMT2ACXCR3CYP1A2 | |
| SCHEMBL29088950 | 0.87 | MEN1 (0.44) | NR1H2NR1H3GPR119MEN1KMT2A | |
| SCHEMBL26914941 | 0.86 | NR1H2 (0.46) | NR1H2NR1H3GPR119MEN1KMT2A | |
| SCHEMBL29088853 | 0.86 | NR1H2 (0.46) | NR1H2NR1H3GPR119MEN1KMT2A | |
| SCHEMBL26914913 | 0.86 | NR1H2 (0.46) | NR1H2NR1H3GPR119MEN1KMT2A | |
| SCHEMBL29274217 | 0.85 | GPR119 (0.47) | GPR119METPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117083274-A | Fused ring heterocyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-115677664-A | Pyridazinones as PARP7 inhibitors | 武汉人福创新药物研发中心有限公司 | 2023-02-03 | — | — | CN | disclosed |