Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.57 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.57 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29754973 | 1.00 | KCNN4 (0.57) | KCNN4KCNA3MIFMMP2DRD3 | |
| SCHEMBL28973111 | 0.91 | KCNN4 (0.62) | KCNN4KCNA3MIFMMP2ACHE | |
| SCHEMBL29754844 | 0.91 | KCNN4 (0.62) | KCNN4KCNA3MIFMMP2ACHE | |
| SCHEMBL29754934 | 0.87 | KCNN4 (0.55) | KCNN4KCNA3MIFMMP2ACHE | |
| SCHEMBL28973132 | 0.87 | KCNN4 (0.55) | KCNN4KCNA3MIFMMP2ACHE | |
| SCHEMBL28973159 | 0.82 | KCNN4 (0.47) | KCNN4KCNA3MIFACHEDHODH | |
| SCHEMBL29754772 | 0.80 | KCNN4 (0.57) | KCNN4KCNA3MIFMMP2TP53 | |
| SCHEMBL28973105 | 0.80 | KCNN4 (0.57) | KCNN4KCNA3MIFMMP2TP53 | |
| SCHEMBL29754785 | 0.79 | MMP2 (0.47) | KCNN4KCNA3MIFMMP2LMNA | |
| SCHEMBL28973103 | 0.79 | MMP2 (0.47) | KCNN4KCNA3MIFMMP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109836384-B | Preparation method of 3-arylmethylene-2, 3-dihydro-4 (1H) -quinolinone | 上海应用技术大学 | 2022-07-08 | — | — | CN | disclosed |