Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29754844 | 0.83 | KCNN4 (0.62) | KCNN4KCNA3MIFACHEMEN1 | |
| SCHEMBL28973111 | 0.83 | KCNN4 (0.62) | KCNN4KCNA3MIFACHEMEN1 | |
| SCHEMBL28973113 | 0.82 | KCNN4 (0.57) | KCNN4KCNA3MIFACHEDHODH | |
| SCHEMBL29754973 | 0.82 | KCNN4 (0.57) | KCNN4KCNA3MIFACHEDHODH | |
| SCHEMBL28973132 | 0.80 | KCNN4 (0.55) | KCNN4KCNA3MIFACHEMEN1 | |
| SCHEMBL29754934 | 0.80 | KCNN4 (0.55) | KCNN4KCNA3MIFACHEMEN1 | |
| SCHEMBL29754853 | 0.78 | ACHE (0.49) | KCNN4KCNA3MIFACHEDHODH | |
| SCHEMBL28973163 | 0.78 | ACHE (0.49) | KCNN4KCNA3MIFACHEDHODH | |
| SCHEMBL28973105 | 0.73 | KCNN4 (0.57) | KCNN4KCNA3MIFMEN1KMT2A | |
| SCHEMBL7336078 | 0.72 | MEN1 (0.42) | KCNN4KCNA3HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109836384-B | Preparation method of 3-arylmethylene-2, 3-dihydro-4 (1H) -quinolinone | 上海应用技术大学 | 2022-07-08 | — | — | CN | disclosed |