SCHEMBL28973797

SCHEMBL28973797

CC(I)Cc1ccc(Cl)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.61
SLC6A3 Q01959 2/20 0.61
SLC6A4 P31645 2/20 0.54
IDO1 P14902 2/20 0.42
ACACB O00763 1/20 0.41
TAAR1 Q96RJ0 2/20 0.40
HTR2A P28223 1/20 0.40
HRH1 P35367 1/20 0.40
HTR2B P41595 1/20 0.40
CHRNA4 P43681 1/20 0.40
ADRB2 P07550 1/20 0.39
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
CYP3A4 P08684 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
NFKB1 P19838 1/20 0.39
CYP2C19 P33261 1/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19546067 0.81 IDO1 (0.48) SLC6A2SLC6A3IDO1ACACBHTR2A
SCHEMBL764989 0.80 SLC6A2 (0.67) SLC6A2SLC6A3SLC6A4IDO1HTR2A
SCHEMBL2326795 0.78 SLC6A2 (0.64) SLC6A2SLC6A3SLC6A4IDO1ACACB
SCHEMBL29327972 0.78 TP53 (0.42) ACACBTAAR1PPARGPPARACYP1A2
SCHEMBL27844428 0.77 SLC6A2 (0.57) SLC6A2SLC6A3SLC6A4IDO1ACACB
SCHEMBL13898915 0.76 TAAR1 (0.61) SLC6A2TAAR1CYP3A4CYP1A2CYP2C9
SCHEMBL3037011 0.76 SLC6A2 (0.61) SLC6A2SLC6A3SLC6A4IDO1ACACB
SCHEMBL4158699 0.76 SLC6A2 (0.61) SLC6A2SLC6A3SLC6A4IDO1ACACB
SCHEMBL22229845 0.76 SLC6A2 (1.00) SLC6A2SLC6A3SLC6A4TAAR1CYP2A6
SCHEMBL4010409 0.76 SLC6A2 (0.61) SLC6A2SLC6A3SLC6A4IDO1ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114716296-B Efficient halogenation synthesis method of alkyl halide 润药仁智(北京)科技有限公司 2023-12-12 CN disclosed
CN-114716296-A Efficient halogenation synthesis method of alkyl halide 北京大学 2022-07-08 CN disclosed