Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974087 | 0.94 | KDM4E (0.38) | PDK2PDK4DRD2DRD4DRD3 | |
| SCHEMBL30280912 | 0.84 | DRD2 (0.47) | PDK2PDK4DRD2DRD4DRD3 | |
| SCHEMBL8581394 | 0.81 | PDK2 (0.37) | PDK2PDK4DRD2DRD4DRD3 | |
| SCHEMBL28060622 | 0.80 | TDP1 (0.40) | PDK2PDK4DRD2DRD4DRD3 | |
| SCHEMBL30281099 | 0.78 | DRD2 (0.45) | PDK2PDK4DRD2DRD4DRD3 | |
| SCHEMBL5951054 | 0.77 | CA12 (0.46) | PDK2PDK4KDM4EPTGER4ALDH1A1 | |
| SCHEMBL30281075 | 0.77 | ALDH1A1 (0.39) | PDK2PDK4DRD2DRD4DRD3 | |
| SCHEMBL8583657 | 0.77 | SCN9A (0.36) | PDK2PDK4DRD2DRD4DRD3 | |
| SCHEMBL6961793 | 0.76 | HTR2C (0.40) | PDK2PDK4KDM4EPTGER4ALDH1A1 | |
| SCHEMBL8583580 | 0.76 | KDM4E (0.37) | PDK2PDK4DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |