Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | PLAU | P00749 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610407 | 0.83 | SMN1; SMN2 (0.39) | SMN1; SMN2KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL5813872 | 0.80 | PDE4A (0.41) | SMN1; SMN2KDM4EMAPTALDH1A1F2 | |
| SCHEMBL21960986 | 0.75 | KDM4E (0.36) | SMN1; SMN2KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL4037598 | 0.75 | MAPT (0.36) | SMN1; SMN2KDM4EMAPTALDH1A1F2 | |
| SCHEMBL3500157 | 0.73 | OPRK1 (0.38) | ALDH1A1HPGDPOLB | |
| SCHEMBL21960873 | 0.72 | KMT2A (0.35) | MAPTALDH1A1POLBSLC6A3SIRT6 | |
| SCHEMBL23910436 | 0.71 | ALDH1A1 (0.36) | KDM4EMAPTALDH1A1F2PLAU | |
| SCHEMBL18546508 | 0.71 | ALDH1A1 (0.50) | SMN1; SMN2KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL8343462 | 0.71 | MAPT (0.41) | SMN1; SMN2MAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL24917 | 0.69 | ALDH1A1 (0.44) | SMN1; SMN2KDM4EMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |