SCHEMBL28974259

SCHEMBL28974259

NC(=O)CCn1c(=O)[nH]c(=O)n(CCC(N)=O)c1=O

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.68
PDE4A P27815 2/20 0.43
PDE4B Q07343 2/20 0.43
PDE4C Q08493 2/20 0.43
PDE4D Q08499 2/20 0.43
KDM4E B2RXH2 2/20 0.43
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.36
CAPN1 P07384 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
PARP1 P09874 3/20 0.35
GAA P10253 1/20 0.34
WEE1 P30291 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11721186 0.84 KDM4E (0.50) APEX1PDE4APDE4BPDE4CPDE4D
SCHEMBL677227 0.81 APEX1 (1.00) APEX1PDE4APDE4BPDE4CPDE4D
SCHEMBL24682696 0.75 APEX1 (0.61) APEX1KDM4EALDH1A1LMNA
SCHEMBL22186985 0.75 APEX1 (0.61) APEX1KDM4EMAPK1ALDH1A1HPGD
SCHEMBL6520401 0.73 APEX1 (0.78) APEX1KDM4EMAPK1ALDH1A1HPGD
SCHEMBL29251524 0.73 APEX1 (0.82) APEX1PDE4APDE4BPDE4CPDE4D
SCHEMBL5198850 0.73 APEX1 (0.54) APEX1SMN1; SMN2L3MBTL1
SCHEMBL838140 0.73 APEX1 (0.59) APEX1PDE4APDE4BPDE4CPDE4D
SCHEMBL29251518 0.71 APEX1 (0.77) APEX1PDE4APDE4BPDE4CPDE4D
SCHEMBL29251522 0.71 APEX1 (0.79) APEX1PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850661-A Transparent environment-friendly intrinsic flame-retardant epoxy resin material and preparation method and application thereof 华南理工大学 2023-03-28 CN disclosed