SCHEMBL677227

SCHEMBL677227

O=C(O)CCn1c(=O)[nH]c(=O)n(CCC(=O)O)c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 2/20 1.00
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 2/20 0.51
HPGD P15428 1/20 0.51
MAPT P10636 1/20 0.44
PDE4A P27815 1/20 0.42
PDE4B Q07343 1/20 0.42
PDE4C Q08493 1/20 0.42
PDE4D Q08499 1/20 0.42
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41
FABP3 P05413 1/20 0.41
FABP4 P15090 1/20 0.41
FABP5 Q01469 1/20 0.41
PKM P14618 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CMA1 P23946 2/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29251524 0.91 APEX1 (0.82) APEX1KDM4EALDH1A1HPGDMAPT
SCHEMBL29251522 0.88 APEX1 (0.79) APEX1KDM4EALDH1A1HPGDMAPT
SCHEMBL6520401 0.88 APEX1 (0.78) APEX1KDM4EALDH1A1HPGDMAPK1
SCHEMBL29251518 0.88 APEX1 (0.77) APEX1KDM4EALDH1A1HPGDMAPT
SCHEMBL113643 0.84 APEX1 (0.71) APEX1KDM4EALDH1A1HPGDMAPT
SCHEMBL4188327 0.83 APEX1 (0.70) APEX1KDM4EALDH1A1HPGDMAPT
SCHEMBL28974259 0.81 APEX1 (0.68) APEX1KDM4EALDH1A1HPGDPDE4A
SCHEMBL11375382 0.78 APEX1 (0.63) APEX1KDM4EALDH1A1HPGDMAPT
SCHEMBL29251517 0.77 APEX1 (0.62) APEX1KDM4EALDH1A1HPGDMAPK1
SCHEMBL6522899 0.77 APEX1 (0.63) APEX1KDM4EALDH1A1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114558621-B Photo-catalyst and method for uranyl isocyanurate di (2-carboxyethyl) ester complex 西安医学院 2024-07-30 CN claimed
EP-4063061-B1 FLUX AND SOLDER PASTE SENJU METAL INDUSTRY CO (JP) 2024-04-24 EP claimed
EP-3964594-B1 FLUX AND SOLDER PASTE KOKI KK (JP) 2024-04-17 EP claimed
CN-115947972-B Low-heat-conductivity soft melamine foam and preparation method thereof 华东理工大学 2024-04-05 CN claimed
CN-114163786-B Degradable stone plastic master batch and preparation method thereof 深圳威尔美新材料科技有限公司 2024-01-19 CN claimed
US-11806818-B2 Flux and solder paste KOKI COMPANY LIMITED (JP) 2023-11-07 US claimed
CN-115947972-A Low-thermal-conductivity soft melamine foam and preparation method thereof 华东理工大学 2023-04-11 CN claimed
CN-115340846-A Durable degradable dust emission inhibitor 潍坊工程职业学院 2022-11-15 CN claimed
US-20220266397-A1 FLUX AND SOLDER PASTE KOKI COMPANY LIMITED (JP) 2022-08-25 US claimed
CN-113766992-B Flux and solder paste 株式会社弘辉 2022-06-10 CN claimed
CN-111268939-A Environment-friendly clean water concrete pumping agent and preparation method thereof 路雪芹 2020-06-12 CN claimed
CN-111234520-A Wire and cable protective material and preparation method thereof 何先鹏 2020-06-05 CN claimed
EP-3650164-A1 FLUX AND SOLDERING MATERIAL Koki Company Limited (JP) 2020-05-13 EP claimed
EP-1352921-B1 EXTRUDED STYRENE RESIN FOAM AND PROCESS FOR PRODUCING THE SAME KANEKA CORP (JP) 2007-02-14 EP claimed
US-6841581-B2 Extruded styrene resin foam and process for producing the same KANEKA CORPORATION (JP) 2005-01-11 US claimed
US-20030220408-A1 Extruded styrene resin foam and process for producing the same KANEKA CORPORATION 2003-11-27 US claimed
EP-1352921-A1 EXTRUDED STYRENE RESIN FOAM AND PROCESS FOR PRODUCING THE SAME KANEKA CORPORATION (JP) 2003-10-15 EP claimed
US-20030191203-A1 Extruded styrene resin foams and methods for producing the same KANEKA CORPORATION (JP) 2003-10-09 US claimed
US-6569912-B1 Comprises hydrocarbons as blowing agents; flameproofing; environmental compatibility; thermal insulative properties KANEKA CORPORATION (JP) 2003-05-27 US claimed
EP-1164158-A1 EXTRUDED STYRENE RESIN FOAM AND PROCESS FOR PRODUCING THE SAME KANEKA CORPORATION (JP) 2001-12-19 EP claimed