Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974517 | 1.00 | HDAC8 (0.44) | HDAC8SCN9ACMA1CHRM2CHRM1 | |
| SCHEMBL29139696 | 0.94 | CHRM2 (0.44) | HDAC8SCN9ACHRM2CHRM1CHRM3 | |
| SCHEMBL23486470 | 0.94 | CHRM2 (0.44) | HDAC8SCN9ACHRM2CHRM1CHRM3 | |
| SCHEMBL28974559 | 0.91 | HDAC8 (0.46) | HDAC8SCN9ACMA1HRH2HRH1 | |
| SCHEMBL28974568 | 0.91 | HDAC8 (0.46) | HDAC8SCN9ACMA1HRH2HRH1 | |
| SCHEMBL23486788 | 0.89 | CHRM2 (0.40) | HDAC8SCN9ACHRM2CHRM1CHRM3 | |
| SCHEMBL28974567 | 0.88 | HDAC8 (0.44) | HDAC8SCN9ACMA1PABPC1CTSS | |
| SCHEMBL28974565 | 0.88 | HDAC8 (0.44) | HDAC8SCN9ACMA1PABPC1CTSS | |
| SCHEMBL28974406 | 0.88 | HDAC8 (0.44) | HDAC8SCN9ACMA1HRH2HRH1 | |
| SCHEMBL28974450 | 0.88 | SCN9A (0.47) | HDAC8SCN9ACMA1PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728917-B | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |