Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974947 | 1.00 | CTSS (0.52) | CTSSCTSKCA2MEN1GAA | |
| SCHEMBL23106074 | 0.88 | CTSK (0.50) | CTSSCTSKCA2MEN1GAA | |
| SCHEMBL20328119 | 0.87 | CTSK (0.60) | CTSSCTSKCA2MEN1GAA | |
| SCHEMBL22525018 | 0.87 | CTSK (0.60) | CTSSCTSKCA2MEN1GAA | |
| SCHEMBL17581833 | 0.87 | CTSS (0.52) | CTSSCTSKCA2MEN1GAA | |
| SCHEMBL12283739 | 0.87 | CTSS (0.52) | CTSSCTSKCA2MEN1GAA | |
| SCHEMBL17902991 | 0.87 | CTSS (0.52) | CTSSCTSKCA2MEN1GAA | |
| SCHEMBL25488736 | 0.87 | CTSS (0.49) | CTSSCTSKCA2MEN1GAA | |
| SCHEMBL13436631 | 0.87 | CTSS (0.52) | CTSSCTSKCA2MEN1GAA | |
| SCHEMBL14012280 | 0.87 | CTSS (0.52) | CTSSCTSKCA2MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728077-A | MCL-1 inhibitor antibody-drug conjugates and methods of use | 诺华股份有限公司 | 2022-07-08 | — | — | CN | disclosed |