Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | LPL | P06858 | 4/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1989062 | 0.87 | FFAR1 (0.50) | FFAR1LPLLIPGIRAK4AAK1 | |
| SCHEMBL875957 | 0.82 | FFAR1 (0.51) | FFAR1LPLLIPGIRAK4 | |
| SCHEMBL17815970 | 0.81 | FFAR1 (0.50) | FFAR1LPLLIPGIRAK4AAK1 | |
| SCHEMBL19713715 | 0.81 | FFAR1 (0.50) | FFAR1LPLLIPGIRAK4AAK1 | |
| SCHEMBL15416423 | 0.80 | FFAR1 (0.50) | FFAR1LPLLIPGIRAK4AAK1 | |
| SCHEMBL29171601 | 0.80 | FFAR1 (0.47) | FFAR1LPLLIPGIRAK4AAK1 | |
| SCHEMBL17005480 | 0.79 | FFAR1 (0.52) | FFAR1LPLLIPGIRAK4AAK1 | |
| SCHEMBL17815976 | 0.79 | FFAR1 (0.49) | FFAR1LPLLIPGIRAK4AAK1 | |
| SCHEMBL22585841 | 0.79 | FFAR1 (0.49) | FFAR1LPLLIPGIRAK4AAK1 | |
| SCHEMBL17801114 | 0.78 | FFAR1 (0.51) | FFAR1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116987080-A | Macrocyclic compounds with heterocyclic P2' groups as factor XIA inhibitors | 百时美施贵宝公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-116802184-A | Pyrazolothiazole carboxamides and their use as PDGFR inhibitors | 埃科特莱茵药品有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-110845498-B | Macrocyclic compounds having heterocyclic P2' groups as factor XIA inhibitors | 百时美施贵宝公司 | 2023-02-17 | — | — | CN | disclosed |