Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | CAMK1D | Q8IU85 | 3/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28976931 | 0.86 | SCN10A (0.40) | SCN10ACAMK1DPARP1PARP2MAPK8 | |
| SCHEMBL28976382 | 0.85 | SCN10A (0.39) | SCN10ACAMK1DPARP1PARP2MAPK8 | |
| SCHEMBL28976616 | 0.82 | SCN10A (0.38) | SCN10ACAMK1DPARP1PARP2GPR52 | |
| SCHEMBL28976510 | 0.82 | IRAK4 (0.41) | SCN10A | |
| SCHEMBL28976419 | 0.81 | KDM4E (0.40) | SCN10APARP1PARP2GPR52KDM4E | |
| SCHEMBL28976476 | 0.79 | SCN10A (0.41) | SCN10ACAMK1DPARP1PARP2MAPK8 | |
| SCHEMBL28976697 | 0.73 | SCN10A (0.37) | SCN10APARP1PARP2KDM1AMAOB | |
| SCHEMBL28976949 | 0.73 | CAMK1D (0.40) | SCN10ACAMK1DPARP1PARP2MAPK8 | |
| SCHEMBL28976707 | 0.72 | CAMK1D (0.39) | SCN10ACAMK1DPARP1PARP2MAPK8 | |
| SCHEMBL28976633 | 0.70 | DGAT1 (0.38) | SCN10APARP1PARP2FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115884810-A | Imidazopyridazines as IL-17 modulators | 詹森药业有限公司 | 2023-03-31 | — | — | CN | disclosed |