Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 10/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 6/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.30 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17497128 | 0.88 | DGAT1 (0.39) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL28976697 | 0.85 | SCN10A (0.37) | SCN10ADGAT1SOAT1FAAHCHRM2 | |
| SCHEMBL28976633 | 0.82 | DGAT1 (0.38) | SCN10ADGAT1SOAT1FAAHCHRM2 | |
| SCHEMBL28976577 | 0.78 | SCN10A (0.33) | SCN10AFFAR2OPRM1 | |
| SCHEMBL28976333 | 0.77 | OPRM1 (0.32) | PDE10AFFAR2POLBROCK2ROCK1 | |
| SCHEMBL28976419 | 0.75 | KDM4E (0.40) | SCN10AROCK2ROCK1 | |
| SCHEMBL28976746 | 0.72 | POLB (0.33) | POLBOPRM1 | |
| SCHEMBL28976931 | 0.71 | SCN10A (0.40) | SCN10AFFAR2ROCK2 | |
| SCHEMBL17497132 | 0.71 | POLB (0.36) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL7135206 | 0.70 | POLB (0.42) | DGAT1SOAT1FAAHCHRM2DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115884810-A | Imidazopyridazines as IL-17 modulators | 詹森药业有限公司 | 2023-03-31 | — | — | CN | disclosed |