Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | CAMK1D | Q8IU85 | 2/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | AKT2 | P31751 | 1/20 | 0.30 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974193 | 0.74 | RET (0.33) | PARP1PARP2 | |
| SCHEMBL30281265 | 0.71 | JAK2 (0.35) | PARP1PARP2 | |
| SCHEMBL28974169 | 0.70 | KDM1A (0.36) | PARP1PARP2 | |
| SCHEMBL28976439 | 0.70 | PARP1 (0.31) | PARP1PARP2 | |
| SCHEMBL28976697 | 0.70 | SCN10A (0.37) | PARP1PARP2SCN10AFFAR2 | |
| SCHEMBL28976633 | 0.70 | DGAT1 (0.38) | PARP1PARP2SCN10AFFAR2 | |
| SCHEMBL29252887 | 0.70 | KDM1A (0.34) | PARP1PARP2 | |
| SCHEMBL28976575 | 0.69 | SCN10A (0.37) | PARP1PARP2SCN10AFFAR2 | |
| SCHEMBL28976931 | 0.67 | SCN10A (0.40) | PARP1PARP2SCN10AFFAR2CAMK1D | |
| SCHEMBL28976927 | 0.66 | PARP1 (0.33) | PARP1PARP2SCN10AFFAR2TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115884810-A | Imidazopyridazines as IL-17 modulators | 詹森药业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |