Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FSHR | P23945 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.31 |
| ▸ | RELA | Q04206 | 3/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28167286 | 0.84 | GAA (0.38) | TSHRFSHRGAAALDH1A1KMT2A | |
| SCHEMBL573575 | 0.78 | NFKB1 (0.39) | GAAALDH1A1KMT2ACA1CA2 | |
| SCHEMBL1829582 | 0.78 | CYP17A1 (0.39) | GAAALDH1A1KMT2ACA1CA2 | |
| SCHEMBL4603098 | 0.77 | GAA (0.39) | GAAALDH1A1KMT2ACA1CA2 | |
| SCHEMBL1656241 | 0.74 | NFKB1 (0.41) | GAAALDH1A1KMT2ACA1CA2 | |
| SCHEMBL28269461 | 0.72 | GAA (0.39) | TSHRFSHRGAAKMT2AAPLNR | |
| SCHEMBL28960308 | 0.69 | BTK (0.38) | GAAALDH1A1KMT2ANFKB1NFKB2 | |
| SCHEMBL1551115 | 0.66 | ALDH1A1 (0.40) | GAAALDH1A1KMT2ACA1CA2 | |
| SCHEMBL3344623 | 0.65 | GAA (0.36) | TSHRFSHRGAACA1CA2 | |
| SCHEMBL17102361 | 0.65 | ALDH1A1 (0.56) | TSHRFSHRALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115884810-A | Imidazopyridazines as IL-17 modulators | 詹森药业有限公司 | 2023-03-31 | — | — | CN | disclosed |