Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31551850 | 0.79 | BACE1 (0.41) | BACE1GLANPSR1 | |
| SCHEMBL31048975 | 0.77 | BACE1 (0.42) | BACE1 | |
| SCHEMBL698104 | 0.77 | BACE1 (0.43) | BACE1GLANPSR1POLB | |
| SCHEMBL24535005 | 0.76 | PIK3CA (0.43) | BACE1GLANPSR1 | |
| SCHEMBL29080116 | 0.76 | KDM4E (0.39) | BACE1GLANPSR1 | |
| SCHEMBL29679997 | 0.76 | PIK3CA (0.43) | BACE1GLANPSR1 | |
| SCHEMBL29679895 | 0.76 | KDM4E (0.39) | BACE1GLANPSR1 | |
| SCHEMBL411648 | 0.75 | BACE1 (0.40) | BACE1GLANPSR1 | |
| SCHEMBL25353819 | 0.74 | L3MBTL1 (0.40) | BACE1GLANPSR1POLB | |
| SCHEMBL8320979 | 0.73 | BACE1 (0.42) | BACE1GLANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894198-B | Qulipta Process for the preparation of 1- (2, 3, 6-trifluorophenyl) propan-2-one, a key intermediate | 浙江永太科技股份有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-115894198-A | Preparation method of key intermediate 1- (2, 3, 6-trifluorophenyl) propane-2-ketone of Qulipta | 浙江永太科技股份有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115894198-B | Qulipta Process for the preparation of 1- (2, 3, 6-trifluorophenyl) propan-2-one, a key intermediate | 浙江永太科技股份有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-115894198-A | Preparation method of key intermediate 1- (2, 3, 6-trifluorophenyl) propane-2-ketone of Qulipta | 浙江永太科技股份有限公司 | 2023-04-04 | — | — | CN | disclosed |