Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL747022 | 0.84 | ALDH1A1 (0.32) | — | |
| SCHEMBL261996 | 0.77 | NQO2 (0.31) | — | |
| SCHEMBL491265 | 0.77 | HSD17B10 (0.34) | CA2CA4 | |
| SCHEMBL491242 | 0.76 | ALDH1A1 (0.43) | CA2CA4 | |
| SCHEMBL817524 | 0.75 | — | — | |
| SCHEMBL2347540 | 0.74 | — | — | |
| SCHEMBL19208031 | 0.74 | TDP1 (0.33) | — | |
| SCHEMBL1638424 | 0.71 | TUBB4A (0.32) | — | |
| SCHEMBL491456 | 0.71 | HDAC4 (0.31) | — | |
| SCHEMBL1401617 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916748-A | Indole derivatives as alpha-1 antitrypsin modulators for the treatment of alpha-1 antitrypsin deficiency (AATD) | 弗特克斯药品有限公司 | 2023-04-04 | — | — | CN | disclosed |