Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938102 | 0.83 | KMT2A (0.47) | MEN1KMT2ASMN1; SMN2BACE1ALDH1A1 | |
| SCHEMBL14782202 | 0.82 | KMT2A (0.46) | MEN1KMT2ASMN1; SMN2BACE1ALDH1A1 | |
| SCHEMBL14782163 | 0.81 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2BACE1ALDH1A1 | |
| SCHEMBL16094929 | 0.77 | ALDH1A1 (0.56) | MEN1KMT2ASMN1; SMN2BACE1ALDH1A1 | |
| SCHEMBL1289600 | 0.77 | ALDH1A1 (0.49) | MEN1KMT2ASMN1; SMN2BACE1ALDH1A1 | |
| SCHEMBL3105068 | 0.77 | SMN1; SMN2 (0.51) | MEN1KMT2ASMN1; SMN2BACE1ALDH1A1 | |
| SCHEMBL5051522 | 0.77 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2BACE1ALDH1A1 | |
| SCHEMBL3750320 | 0.76 | HSD17B10 (0.60) | MEN1KMT2ASMN1; SMN2BACE1ALDH1A1 | |
| SCHEMBL22134502 | 0.75 | KMT2A (0.45) | MEN1KMT2ASMN1; SMN2BACE1ALDH1A1 | |
| SCHEMBL22320958 | 0.75 | SMN1; SMN2 (0.51) | MEN1KMT2ASMN1; SMN2BACE1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988093-B | Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine | 广东东阳光药业有限公司 | 2023-04-07 | — | — | CN | disclosed |