Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095591 | 0.86 | MAPT (0.55) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL14938102 | 0.85 | KMT2A (0.47) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL14782202 | 0.84 | KMT2A (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL1289600 | 0.82 | ALDH1A1 (0.49) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL28978972 | 0.81 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL27982502 | 0.80 | RAB9A (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL7649455 | 0.80 | PTPN1 (0.47) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL3105068 | 0.79 | SMN1; SMN2 (0.51) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL5051522 | 0.79 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL22134502 | 0.77 | KMT2A (0.45) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3670523-A1 | 5-METHOXY. 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | Agilent Technologies, Inc. (US) | 2020-06-24 | — | — | EP | disclosed |
| EP-2970366-A1 | NUCLEOTIDE ANALOGS FOR SEQUENCING | Ibis Biosciences, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014150851-A1 | NUCLEOTIDE ANALOGS FOR SEQUENCING | IBIS BIOSCIENCES, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| EP-2755984-A1 | 5-METHOXY. 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | Lasergen, Inc. (US) | 2014-07-23 | — | — | EP | disclosed |
| WO-2013040257-A1 | 5-METHOXY. 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | LASERGEN, INC. (US) | 2013-03-21 | — | — | WO | disclosed |