Mannitol

Mannitol

SCHEMBL28979520

O=NO.OCC(O)C(O)C(O)C(O)CO

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.69
L3MBTL1 Q9Y468 2/20 0.69
TDP1 Q9NUW8 1/20 0.65
PDE4A P27815 1/20 0.52
USP2 O75604 1/20 0.48
SLCO1B1 Q9Y6L6 1/20 0.48
KDM4E B2RXH2 2/20 0.46
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.33
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
TOP1 P11387 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sorbitol SCHEMBL29468856 1.00 LMNA (0.69) LMNAL3MBTL1TDP1PDE4AUSP2
Mannitol SCHEMBL28714074 0.92 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AUSP2
Mannitol SCHEMBL13187369 0.83 LMNA (1.00) LMNAL3MBTL1TDP1PDE4AUSP2
Sorbitol SCHEMBL763 0.83 LMNA (1.00) LMNAL3MBTL1TDP1PDE4AUSP2
Mannitol SCHEMBL12455929 0.83 LMNA (1.00) LMNAL3MBTL1TDP1PDE4AUSP2
Mannitol SCHEMBL23066399 0.83 LMNA (1.00) LMNAL3MBTL1TDP1PDE4AUSP2
Mannitol SCHEMBL2477078 0.83 LMNA (1.00) LMNAL3MBTL1TDP1PDE4AUSP2
Mannitol SCHEMBL21837180 0.83 LMNA (1.00) LMNAL3MBTL1TDP1PDE4AUSP2
Mannitol SCHEMBL20594083 0.83 LMNA (1.00) LMNAL3MBTL1TDP1PDE4AUSP2
Mannitol SCHEMBL20567656 0.83 LMNA (1.00) LMNAL3MBTL1TDP1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115884758-A Nitric oxide or nitric oxide-releasing compositions for the treatment of SARS-CoV and SARS-CoV-2 三十呼吸有限公司 2023-03-31 CN disclosed