Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | ANPEP | P15144 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | HTRA1 | Q92743 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29458800 | 1.00 | MMP2 (0.53) | MMP2ANPEPCTSSCTSKAAK1 | |
| SCHEMBL29398426 | 1.00 | MMP2 (0.53) | MMP2ANPEPCTSSCTSKAAK1 | |
| SCHEMBL21119318 | 1.00 | MMP2 (0.53) | MMP2ANPEPCTSSCTSKAAK1 | |
| SCHEMBL19745166 | 0.92 | CTSS (0.48) | MMP2ANPEPCTSSCTSKAAK1 | |
| SCHEMBL21536101 | 0.92 | CTSS (0.48) | MMP2ANPEPCTSSCTSKAAK1 | |
| SCHEMBL19744563 | 0.92 | CTSS (0.48) | MMP2ANPEPCTSSCTSKAAK1 | |
| SCHEMBL19744560 | 0.92 | CTSS (0.48) | MMP2ANPEPCTSSCTSKAAK1 | |
| SCHEMBL19745167 | 0.92 | CTSS (0.48) | MMP2ANPEPCTSSCTSKAAK1 | |
| SCHEMBL21536102 | 0.86 | MMP2 (0.57) | MMP2ANPEPCTSKHTRA1 | |
| SCHEMBL21506053 | 0.84 | CTSS (0.50) | CTSSCTSKAAK1HTRA1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563033-B | Aliphatic prolinamide derivatives | 奥瑞恩眼科有限责任公司 | 2023-04-04 | — | — | CN | disclosed |