Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | REN | P00797 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669890 | 1.00 | ACE (0.60) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL28866775 | 1.00 | ACE (0.60) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL4669888 | 1.00 | ACE (0.60) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL497515 | 1.00 | ACE (0.60) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL3369452 | 1.00 | ACE (0.60) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL4669921 | 1.00 | ACE (0.60) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL3780597 | 1.00 | ACE (0.60) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL1221172 | 1.00 | ACE (0.60) | ACELMNAABCB11MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7264173 | 0.99 | ACE (0.59) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL11041388 | 0.99 | ACE (0.59) | ACELMNAABCB11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689611-A | METHOD FOR PRODUCING ORGANIC COMPOUND | 株式会社钟化 | 2019-04-26 | — | — | CN | claimed |
| CN-105800769-B | A kind of device and its processing method of biology Wheel-type processing toxic organic compound sewage | 徐州工程学院 | 2019-03-22 | — | — | CN | claimed |
| CN-109021064-A | A kind of preparation method of enalapril maleate | 扬子江药业集团有限公司 | 2018-12-18 | — | — | CN | claimed |
| CN-106186488-A | A kind of Integration Method processes equipment and the processing method thereof of harmful substance in sewage | 徐州工程学院 | 2016-12-07 | — | — | CN | claimed |
| CN-105800769-A | Biological wheel disc type device for treating toxic organic matter sewage and treatment method thereof | 徐州工程学院 | 2016-07-27 | — | — | CN | claimed |
| CN-104513292-A | Preparation method of ramipril | SHANGDONG NEW TIME PHARM PROD | 2015-04-15 | — | — | CN | claimed |
| CN-103396333-A | Preparation method of general intermediate ECPPA of ACEI (angiotensin converting enzyme inhibitor) medicines | DALIAN HAIRONG TECHNOLOGY DEV CO LTD | 2013-11-20 | — | — | CN | claimed |
| EP-1262480-B2 | Process for the preparation of N-carboxyanhydrides of amino acids | ISOCHEM SA (FR) | 2010-08-04 | — | — | EP | claimed |
| EP-1262480-B1 | Process for the preparation of N-carboxyanhydrides of amino acids | ISOCHEM SA (FR) | 2005-09-07 | — | — | EP | claimed |
| EP-1201659-B1 | Process for the preparation of N-carboxyanhydrides | ISOCHEM SA (FR) | 2004-05-19 | — | — | EP | claimed |
| EP-0789029-B1 | Improved procedure for the preparation of pure(S,S)-N-(1-Ethoxycarbonyl-3-phenylprophyl)-alanin). | DSM FINE CHEM AUSTRIA GMBH (AT) | 2003-09-10 | — | — | EP | claimed |
| US-6603016-B2 | Reaction of alpha-, beta- or gamma- amino acid or one of its salts with phosgene, diphosgene and/or triphosgene in a solvent; a portion is carried out under a pressure of < 1000 mbar | ISOCHEM (FR) | 2003-08-05 | — | — | US | claimed |
| US-20020183551-A1 | Process for the preparation of N-carboxyanhydrides | ISOCHEM (FR) | 2002-12-05 | — | — | US | claimed |
| EP-1262480-A1 | Process for the preparation of N-carboxyanhydrides of amino acids | ISOCHEM (FR) | 2002-12-04 | — | — | EP | claimed |
| US-6479665-B2 | REACTING ALPHA-, BETA- OR GAMMA- AMINO ACID OR OF ONE OF ITS SALTS WITH PHOSGENE, DIPHOSGENE AND/OR TRIPHOSGENE IN A SOLVENT MEDIUM, IN PRESENCE OF UNSATURATED ORGANIC COMPOUND WHICH HAS ONE OR MORE ETHYLENIC DOUBLE BONDS | ISOCHEM (FR) | 2002-11-12 | — | — | US | claimed |
| US-20020082431-A1 | Process for the preparation of N-carboxyanhydrides | ISOCHEM (FR) | 2002-06-27 | — | — | US | claimed |
| EP-1201659-A1 | Process for the preparation of N-carboxyanhydrides | ISOCHEM (FR) | 2002-05-02 | — | — | EP | claimed |
| US-5756812-A | Process for the preparation of pure (S,S)-N-(1-ethoxycarbonyl-3-phenylpropyl) alanine | DSM CHEMIE LINZ GMBH (AT) | 1998-05-26 | — | — | US | claimed |
| JP-1047754-A | — | — | None | — | — | JP | disclosed |
| EP-0049605-A1 | Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids, salts thereof, pharmaceutical compositions containing the derivatives or salts, and the production of the same | WARNER-LAMBERT COMPANY (US) | 1982-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183551-A1 | Process for the preparation of N-carboxyanhydrides | NPEPPS, DDOST, DNPEP | ACE 2648/4885LMNA 3891/4885ABCB11 1154/4885 |
| US-20020082431-A1 | Process for the preparation of N-carboxyanhydrides | NPEPPS, CPN1, DDOST | ACE 2707/4885LMNA 2292/4885ABCB11 2020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.